Grynszpan Lab

Publications

  1. Highly Sensitive Detection of Cobalt Through Fluorescence Changes in β-Cyclodextrin-Bimane Complexes. By A. Pramanik, S. Amer, F. Grynszpan, and M. Levine. Submitted for publication (2020).

  2. Effective hydroxide transport through dependable polysulfone based membranes negotiated by a triazatriangulenium cation. By J. Thomas, B. Francis, S. Thomas, A. Schechter, and F. Grynszpan. Submitted for publication (2020).

  3. Expedient synthesis and anticancer evaluation of dual-action 9-anilinoacridine methyl triazene chimeras.  By D. Walunj, K. Egarmina, H. Tuchinsky, O. Shpilberg, O. Hershkovitz-Rokah, F. Grynszpan, and G. Gellerman.  Chem. Biol. Drug Des. In press (2020).(2020).

  4. Antimicrobial Peptide Surrogates Based on Freidger Lactam. By M. Kovaliov, G. Zats-Mor, I. Lapidot, R. Krieger, F. Grynzspan, G. Gellerman, A. Albeck, and Sh. Shatzmiller. J. Cancer Res. Oncobiol. 2.2, 1 -5 (2019). DOI: 10.31021/jcro.20192126.

  5. syn-(Me,Me)Bimane as a Structural Building Block in Metal Coordination Architectures. By Y. Diskin-Posner, S. Amer, A. Roy, P. J. Das, F. Grynszpan, and M. Montag. Cryst. Growth Des. 19 (8), 4358-4368 (2019). https://doi.org/10.1021/acs.cgd.9b00089

  6. Quenching of syn-Bimane Fluorescence by Na+ Complexation. By A. Roy, P.J. Das, Y. Diskin-Posner, M. Firer, F. Grynszpan, and M. Montag. New J. Chem. 42, 15541-15545 (2018). DOI: 10.1039/C8NJ01945B
  7. Dihalogen and solvent free preparation of syn-bimane. By I. Neogi, P. J. Das and F. Grynszpan. Synlett. 29 (08), 1043-1046 (2018). DOI: 10.1055/s-0036-1591964.
  8. A two-step strategy to visually identify molecularly imprinted polymers for tagged proteins. By A. Brandis, E. Partouche, T. Yechezkel, Y. Salitra, V. Shkoulev, A. Scherz, and F. Grynszpan. J. Sep. Sci., 40(16), 3358-3367 (2017). DOI: 10.1002/jssc.201700269
  9. syn-Bimane as a Chelating O-Donor Ligand for Palladium(II).  By P.J. Das, Y. Diskin-Posner, M. Firer, M. Montag, and F. Grynszpan. Dalton Trans., 45, 17123-17131 (2016). DOI: 10.1039/C6DT02141G. Highlighted as the cover of the Journal.
  10. Bio-Labile Peptidyl Delivery Systems Towards Sequential Drug Release.
    By E. Ragozin, B. Redko, E. Tuchinsky, A. Rozovsky, A. Albeck, F. Grynszpan and G. Gellerman. Biopolymers: Peptide Synthesis. 106(1), 119–132, (2016). DOI: 10.1002/bip.22794.
  11. Synthesis and in-vitro anticancer evaluation of 1,8-naphthalimide N(4) and S(4)-derivatives combining DNA intercalation and alkylation capabilities.
    By T. Brider, B. Redko, M. Oron-Herman, A. Cohen-Matzlich, G. Gerlitz, G. Gellerman, and F. Grynszpan. Research on Chemical Intermediates, 1-17, (2016). DOI: 10.1007/s11164-015-2115-1.
  12. alpha-Aminoisobutyric acid leads a fluorescent syn-bimane LASER probe across the blood-brain barrier.
    By, I. Lapidot, D. Baranes, A. Pinhasov, G. Gellerman, A. Albeck, F. Grynszpan, and Sh.E. Shatzmiller. Medicinal Chemistry, 12(1), 48-53, (2016). DOI: 10.2174/1573406411666150518105010
  13. 1,4-Dihydropyridine Cationic Peptidomimetics with Broad Antibacterial Activity.
    By I. Lapidot, A. Albeck, G. Gellerman, Sh.E. Shatzmiller and F. Grynszpan. Int. J. Peptide Res. Ther. 21(3), 243-247, (2015). DOI: 10.1007/s10989-015-9460-1.
  14. Three overlooked chemical approaches toward 3-naphthalimide amonafide N-derivatives.
    By T. Brider; B. Redko F. Grynszpan and G. Gellerman, Tetrahedron Letters, 55, 6675–6679 (2014).
  15. Automated Docking with Protein Flexibility in the Design of Femtomolar “Click Chemistry” Inhibitors of Acetylcholinesterase.
    By G.M. Morris, L.G. Green, Z. Radić, P. Taylor, K.B. Sharpless, A.J. Olson, and F. Grynszpan, J. Chem. Inf. Model.,53 (4), 898–906 (2013).
  16. The Reaction of a Bis(spirodienone) Calix[4]arene Derivative with Hydrazine.
    By F. Grynszpan and S. E. Biali, Arkivok, 38-48, (2003).
  17. Mutants of 4-Oxalocrotonate Tautomerase Catalyze the Decarboxylation of Oxaloacetate through an Imine Mechanism.
    By A. Brik, L.J. D’Souza, E. Keinan, F. Grynszpan and P.E. Dawson. ChemBioChem, 3, 845-85, (2002).
  18. Click Chemistry in situ: Acetylcholinesterase as a Molecular-Scale Reaction Vessel for the Selective Assembly of a Femtomolar Inhibitor from an Array of Building Blocks.
    By W.G. Lewis, L.G. Green, F. Grynszpan, Z. Radic, P.R. Carlier, P. Taylor, M.G. Finn, and K.B. Sharpless. Angew. Chem. 114, 1095-1099, (2002). Angew. Chem. Int. Ed., 41, 1053-1057, (2002). (Highlighted in Chem. & Eng. News, Feb. 11, 2002; 80(6), p. 29-34, Cover Story. Highlighted in The Union Tribune, San Diego, City Edition, B1. Highlighted in Nature, Drug Discovery Reviews, 1, 254, (2002), among others).
  19. Prediction of the Protein-Protein Interaction in the LFA-1 I-Domain / ICAM-1 D1-D2 Complex.
    By G.B. Legge, G.M. Morris, M.F. Sanner, Y. Takada, A.J. Olson and F. Grynszpan. Proteins, Struct. Func. Gen. 48, 151-160 (2002).
  20. Multiple Reactive Immunization Towards the Hydrolysis of Organophosphorous Nerve Agents: Hapten Design and Synthesis.
    By H. Huang, W.-G. Han, L. Noodleman and F. Grynszpan. Bioorg. Med. Chem. 9, 3185-3195, (2001).
  21. Stereochemistry of a Spherand-Type Calixarene.
    By K. Agbaria, S.E. Biali,V. Böhmer,J. Brenn,Sh. Cohen,M. Frings, F. Grynszpan, J.McB. Harrowfield,A.N. Sobolev and I. Thondorf J. Org. Chem. 66, 2900-2906, (2001).
  22. Opsin Shift in an Aldolase Antibody.
    By F. Grynszpan and E. Keinan. Bioorg. Med. Chem. Lett. 9, 2419-2425 (1999).
  23. Conformational Studies of Calix[5]arenes Containing a SingleAlkanediylBridge.
    By S. E. Biali, V. Böhmer, I. Columbus, G. Fergurson, C. Grüttner, F. Grynszpan, E. F. Paulus and I. Thondorf. J. Chem. Soc. Perkin Trans 2, 2261-1170 (1998).
  24. Use of Antibodies to Dissect the Components of a Catalytic Event. The Cyclopropenone Hapten.
    By F. Grynszpan and E. Keinan, Chem. Commun., 865-866 (1998).
  25. Spirodienone Calixarene Derivatives as Blocking Groups for Selective Functionalizations: Conformation and Stereodynamics of Monodioxamethylene Calix[4]arene Derivatives.
    By J. Wöhnert, J. Brenn, M. Stoldt, O. Aleksiuk, F. Grynszpan, I. Thondorf and S. E. Biali, J. Org. Chem., 63, 3866-3874 (1998).
  26. An Efficient Sol-Gel Reactor for Antibody Catalyzed Transformations.
    By D. Shabat, F. Grynszpan, S. Saphier, A. Turniansky, D. Avnir and E. Keinan, Chem. Mat.,9, 2258-2260 (1997).
  27. Structure and Equilibration Studies of Bis – and Tris(spirodienone) Derivatives of Medium – Sized Calixarenes.
    By F. Grynszpan and S. E. Biali, J. Org. Chem., 61, 9512-9521 (1996).
  28. Using Antibodies to Perturb the Coordination Sphere of a Transition Metal Complex.
    By P. Ghosh, D. Shabat, S. Kumar, S. C. Sinha, F. Grynszpan, J. Li, L. Noodelman and E. Keinan, Nature, 382, 339-341 (1996). (Summarized in Chem. & Eng. News, July 29, 1996; p. 40, Science/Tech. Concentrates).
  29. Alkanediyl Bridged Calix[4]arenes: Synthesis, Conformational Analysis and Rotational Barriers.
    By S. E. Biali, V. Böhmer, Sh. Cohen, G. Ferguson, C. Grüttner, F. Grynszpan, E. Paulus, I. Thondorf and W. Vogt, J. Am. Chem. Soc., 118, 12938-12949 (1996).
  30. From Calixarenes to Macrocyclic Polyethers.
    By F. Grynszpan and S. E. Biali, J. Chem. Soc., Chem. Commun., 195-196 (1996).
  31. Synthesis and Reactions of Large – Ring Spirodienone Calixarene Derivatives.
    By F. Grynszpan, O. Aleksiuk, and S. E. Biali, Pure and Appl. Chem., 68 (6), 1249-1254 (1996).
  32. Spirodienone Calixarene Derivatives.
    By O. Aleksiuk, F. Grynszpan, A. M. Litwak, and S. E. Biali, New J. Chem., 20, 473-482 (1996).
  33. Preparation, Structure and Stereodynamics of Phosphorus Bridged Calixarenes. “Calixarenes 50th Annivrsary”, pp. 199-221. J. Vicens, Z. Asfari, J. M. Harrowfied, Ed., Kluwer Academic Publishers; Dordrecht/Boston/London, 1995.
    By By O. Aleksiuk, F. Grynszpan and S. E. Biali.
  34. NMR Diffusion Coefficients of p-tert-butylcalix[n]arene Systems.
    By O. Mayzel, O. Aleksiuk, F. Grynszpan and S. E. Biali, Y. Cohen, J. Chem. Soc., Chem. Commun, 1183-1184 (1995).
  35. Large Macrocyclic Rings with Complex Architectures:Polyspirodienone Calix[6]arene Derivatives.
    By F. Grynszpan and S. E. Biali, J. Chem. Soc., Chem. Commun., 2545-2546 (1994).
  36. Calix[4]arenes with AlkylideneBridges, Synthesis and Conformational Properties.
    By C. Grüttner, V. Böhmer, W. Vogt, I. Thondorf, S. E. Biali and F. Grynszpan, Tetrahedron Lett., 35, 6267-6270 (1994).
  37. Preparation, Structure and Stereodynamics of Phosphorus Bridged Calixarenes.
    By O. Aleksiuk, F. Grynszpan and S. E. Biali, J. Inclus. Phenom., 19, 237-256 (1994).
  38. Cyclization and Reductive Cleavage of Monospirodienone Calix[4]arene Derivatives. Trihydroxy-p-tert- butylcalixarene Revisited.
    By F. Grynszpan, O. Aleksiuk and S. E. Biali, J. Org. Chem., 59, 2070-2074 (1994).
  39. Transmission of Internal Rotations: Correlated, Uncorrelated and Localized Disrotatory Rotation in Propeller Chains.
    By A. B. Lindner, F. Grynszpan and S. E. Biali, J. Org. Chem., 58, 6662-6670 (1993).
  40. The Spirodienone Route for Aminodehydroxylation: Monoaminotrihydroxy-p-tert-butylcalix[4]arene.
    By O. Aleksiuk, F. Grynszpan and S. E. Biali, J. Org. Chem., 58, 1994-1996 (1993).
  41. Preparation, Stereochemistry and Reactions of the Bis(spirodienone) Derivatives of p-tert-Butylcalix[4]arene.
    By A. M. Litwak, F. Grynszpan, O. Aleksiuk, Sh. Cohen and S. E. Biali, J. Org. Chem., 58, 393-402 (1993).
  42. Phosphorus Polybridged Calixarenes.
    By F. Grynszpan, O. Aleksiuk and S. E. Biali, J. Chem. Soc., Chem. Commun., 13-16 (1993).
  43. Proximal Intraannular Modifications of Calix[4]arene via its Spirodienone Derivative.
    By O. Aleksiuk, F. Grynszpan and S. E. Biali, J. Chem. Soc., Chem. Commun., 11-13 (1993).
  44. The source of the Intraannular Hydrogens in the Dehydroxylation of Calix[4]arene Diethyl Phosphate Ester Derivatives.
    By F. Grynszpan and S. E. Biali, J. Phys. Org. Chem., 5, 155-159 (1992).
  45. Solution Conformation and Inversion Barrier in Dihydroxycalixarene.
    By F. Grynszpan and S. E. Biali, Tetrahedron Lett., 32, 5155-5158 (1991).
  46. Reductive and Oxidative Reactions of Calix[4]arene Derivatives
    By F. Grynszpan, N. Dinoor and S. E. Biali, Tetrahedron Lett., 32, 1909-1912 (1991).
  47. Partially OH-Depleted Calixarenes.
    By F. Grynszpan, Z. Goren and S. E. Biali, J. Org. Chem., 56, 532-536 (1990).
  1. Novel triazatriangulenium cationic membranes for fuel cell applications. By J. Thomas, B. Francis, S. Thomas, A. Schechter and F. Grynszpan. The 85th Annual Meeting of the Israel Chem. Soc. Binyanei Hauma, Jerusalem, Israel. W-79. February 18-19th, 2020.
  2. A practical approach towards a-iodobimane reactive intermediates. By O. Szumski, J. Karmakar and F. Grynszpan. The 85th Annual Meeting of the Israel Chem. Soc. Binyanei Hauma, Jerusalem, Israel. T-20. February 18-19th, 2020.
  3. Toward a Selective syn-Bimane Fluorescent Probe for Aldolase Class-1. By J. Karmakar and F. Grynszpan. 2nd Alpine Winter Conference on Medicinal and Synthetic Chemistry. St. Anton, Austria. P-008. January 19-23rd, 2020.
  4. syn-[Tetrazole,Me][Me,Me]Bimane: A Potential pH-Sensitive Probe for Tumor Cell Imagining. By J. Karmakar, M. Montag and F. Grynszpan. The 16th Annual Meeting of the Medicinal Chemistry Section of the Israel Chemical Society. WIS, Rehovot, Israel. P#14. June 19th, 2019.
  5. Bimanes reconsidered: From fluorescent dyes to ligands. By P. J. Das, A. Roy, S. Amer, J. Karmakar, T. Burg, Y. Diskin-Posner, M. Firer, F. Grynszpan, and M. Montag. The 84th Annual Meeting of the Israel Chem. Soc. David InterContinental Hotel, Tel-Aviv, Israel. Oral Presentation by M.M.  February 12-13, 2019.
  6. Complexes of syn-(Me,Me)bimane with biorelevant metals: Crystal structures and metal-ion-induced fluorescence quenching. By A. Roy, T. Burg, P. J. Das, Y. Diskin-Posner, M. Firer, F. Grynszpan, M. Montag. The 84th Annual Meeting of the Israel Chem. Soc. David InterContinental Hotel, Tel-Aviv, Israel. T-60.  February 12-13, 2019.
  7.  (Me,Me)bimane as a metal-binding ligand: Complexation and photophysical effects. By S. Amer, A. Roy, P. J. Das, J. Karmakar, Y. Diskin-Posner, F. Grynszpan, M. Montag. The 84th Annual Meeting of the Israel Chem. Soc. David InterContinental Hotel, Tel-Aviv, Israel. T-37.  February 12-13, 2019.

  8. Thioxobimanes: New Ligands for Coinage Metals. POSTER AWARD: 2nd Prize.
    By P.J. Das, A. Roy, J. Karmakar, A. Nandi, S. Kozuch, Y.-Diskin Posner, M. Firer, F. Grynszpan and M. Montag. Frontiers in Chemistry, Armenia October 21st-25th 2018.

  9.  syn-(Me,Me)Bimane: A Fluorescent Ligand for Na+. By A. Roy, P.J. Das, Y. Diskin-Posner, M. Firer, F. Grynszpan, and M. Montag. Inorganic Chemistry, Gordon Research Conference. Biddeford, ME. Oral presentation by A.R. June 16th-17th 2018.

  10. syn-Bimanes as Ligands: A New Role for Old Fluorescent Dyes. A. Roy, P. J. Das, S. Amer, A. Nandi, J. Karmakar, T. Burg, Y. Diskin-Posner, S. Kozuch, M. Firer, F. Grynszpan, M. Montag. Inorganic Chemistry, Gordon Research Conference. June 17th–22th 2018.

  11. Tröger’s Base Decorated Arylketones for Application in PhOLEDs.
    By I. Neogi, P.J. Das, F. Grynszpan. The83rd Annual Meeting of the Israel Chem. Soc. David InterContinental Hotel, Tel-Aviv, Israel. P-125. February 13-14, 2018.
  12. Cl2 (g) Free Synthesis of syn-(Me,Me)Bimane.
    By P.J. Das, I. Neogi, M. Firer, F. Grynszpan. The83rd Annual Meeting of the Israel Chem. Soc. David InterContinental Hotel, Tel-Aviv, Israel. P-101. February 13-14, 2018.
  13. syn-(Me,Me)Bimane: A Fluorescent ligand for Na+.
    By A. Roy, P.J. Das, Y. Diskin-Posner, M. Firer, F. Grynszpan, M. Montag. The83rd Annual Meeting of the Israel Chem. Soc. David InterContinental Hotel, Tel-Aviv, Israel. P-51. February 13-14, 2018.
  14. Biomolecular Catalysts: from Antibodies to Oligopeptides.
    By F. Grynszpan. Chemistry and Beyond; Conference in honor of Prof. Ehud Keinan’s 70. Technion. Invited Lecture. Oct. 19th 2017.
  15. syn-Bimanes tuned as Schiff base fluorescent probes.
    By P.J. Das, I. Neogi, M. Firer and F. Grynszpan. The 14th Annual Meeting of the Medicinal Chemistry Section of the Israel Chemical Society. WIS, Rehovot, Israel. P#39. June 7th, 2017.
  16. Thioxobimanes: Structural and Chelating Studies.
    By P.J. Das, A. Roy, Y. Diskin-Posner, I. Pinkas, A. Nandi, S. Kozuch, M. Firer, M. Montag, and F. Grynszpan. The82nd Annual Meeting of the Israel Chem. Soc. David InterContinental Hotel, Tel-Aviv, Israel. PA #7. February 13-15, 2017.
  17. syn-(Me,Me)bimane: A Fluoroscent Ligand for Biologically Important Alkali and Alkaline Earth Metal Cations.
    By A. Roy, P.J. Das, Y. Diskin-Posner, M. Firer, F. Grynszpan, and M. Montag. The82nd Annual Meeting of the Israel Chem. Soc. David InterContinental Hotel, Tel-Aviv, Israel. PB #43. February 13-15, 2017.
  18. Ol’ Bimane is Learning New Tricks.
    By P.J. Das, A. Roy, Y. Diskin-Posner, I. Pinkas, M. Firer, M. Montag and F. Grynszpan. The82nd Annual Meeting of the Israel Chem. Soc. David InterContinental Hotel, Tel-Aviv, Israel. Invited Lecture, S1 #76. February 13-15, 2017.
  19. Approaches Towards Catalytic Neutralization of Toxic Organophosphate Agents
    By P.J. Das, A. Roy, M. Firer, M. Montag, and F. Grynszpan. Global Young Scientists Summit (GYSS). Singapore University of Technology and Design, January 15-20th 2017.
  20. syn-(Me,Me)Bimane and its thionated analogs: synthesis and coordination chemistry.
    By P.J. Das, A. Roy, M. Montag and F. Grynszpan. The 8th National Chemistry Graduate Students Symposium. Ben Gurion U., Beer-Sheva, Israel. December 8th 2016.
  21. syn-Bimanes as Chalcogen-Donor Ligands for Transition Metals.
    By P.J. Das, Y. Diskin-Posner, M. Firer, M. Montag, and F. Grynszpan. Inorganic Chemistry, Gordon Research Conference. June 19th–24th 2016.
  22. Catalytic Decomposition of Hazardous Organophosphate Agents
    By A. Roy, P.J. Das, M. Firer, F. Grynszpan, and M. Montag. Ariel University Interdisciplinary Natural Sciences Symposium. Ariel U. Ariel, Israel. June 16th 2016
  23. Chemical Modifications of the Bimane Fluorophore.
    By P.J. Das, O. Goldstein, D. Schneiderman, M. Firer, M. Montag and F. Grynszpan Ariel University Interdisciplinary Natural Sciences Symposium. Ariel U. Ariel, Israel. June 16th 2016.
  24. Bio-labile peptidyl delivery systems towards sequential drug release.
    By E. Ragozin, B. Redko, E. Tuchinsky, A. Rozovsky, A. Albeck, F. Grynszpan, and G. Gellerman. 8th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems. Madrid, Spain. March 7-9, 2016.
  25. PdII-Bimane Complexes: First of its Class.
    By P. J. Das, M. Montag, M. Firer, and F. Grynszpan. The 7th National Graduate Students Symposium in Organic Chemistry. Ariel U. Ariel, Israel. December 17th 2015.
  26. Towards Bio-Labile Targeted Peptidyl Delivery Systems with Sequential Drug Release.
    By E. Ragozin, B. Redko, E. Tuchinsky, A. Rozovsky, A. Albeck, F. Grynszpan, and G. Gellerman. The 7th National Graduate Students Symposium in Organic Chemistry. Ariel U. Ariel, Israel. December 17th 2015.
  27. PdII Catalyzed Alkylation of syn-Monobromobimane.
    By P. J. Das, I. Lapidot, Sh. E. Shatzmiller, M. A. Firer and F. Grynszpan. EFMC-ASMC’15 International Symposium on Advances in Synthetic and Medicinal Chemistry. WIS, Rehovot, Israel. November 15th-18th, 2015.
  28. Advanced Anion-Conducting Membranes for Electrochemical Cells.
    By O. BenZazon, F. Grynszpan and A. Schechter. EcoMotion 2014 – 2nd Main Event, Top Ten Student Presentations Session. Sdot Yam, Israel. May 22-23, 2014.
  29. Chemistry-Driven Enzyme-Based Lead Optimization.
    By F. Grynszpan. Invited Lecture at TEVA ASSIA’s monthly seminar, Denmark 2, Petah Tikvah, Israel. September 17th, 2013.
  30. Stimuli Responsive MIPs.
    By E. Partouche, Sh. Gazal, I. Zigelboim, V. Shkoulev, A. Aizicovich and F. Grynszpan. The 78th Annual Meeting of the Israel Chem. Soc. Dan Panorama Hotel, Tel-Aviv, Israel, Day 1 # 91 February 12-13, 2013.
  31. Plastibodies for Biotinylated Proteins.
    By E. Partouche,V. Shkoulev, Y. Salitra, T. Yechezkel and F. Grynszpan. The 1st Israeli-UK Medicinal Chemistry Conference, Weizmann Institute of Science, Rehovot Israel, pp. 48. April 22-23, 2012.
  32. Artificial Polymer Receptors as Tools for Labelled Biomacromolecule Isolation.
    By E. Partouche,V. Shkoulev, Y. Salitra, T. Yechezkel and F. Grynszpan. The 76th Annual Meeting of the Israel Chem. Soc. David –Intercontinental Hotel, Tel-Aviv, Israel, pp. 65. February 09-10, 2011.
  33. Tetracyclic Benzofuran Cannabinoids: an Unexplored Scaffold for Druggable CB2 Selective Modulators.
    By M. Brody, A. Aizikovich, B. Avidor, A. Nudelman, O. Greenberg, A. Avraham, D. Dar, S. Anavi-Goffer, P. David, A. Weksler, A. Richstein, A. Bar Joseph, S. Meilin, I. Alroy, A. Garzon, A. Yacovan and F. Grynszpan. The 71th Annual Meeting of the Israel Chem. Soc. David –Intercontinental Hotel, Tel-Aviv, Israel, pp. 284. February 27-28, 2006.
  34. Looking for a Lead Compound? –Let the Enzyme Decide and Assemble it for You!
    By W. Lewis, L.G. Green, Z. Radic, S. Rostovtsev, P. Taylor, M.G. Finn, F. Grynszpan, and K.B. Sharpless. Discovery 2002: Improving the Process. Hotel Del Coronado, Coronado, CA. March 18-20, 2002.
  35. Lessons from Catalytic Antibodies Applied to Tautomerase Enzymes.
    By E. Keinan, A. Brik, L.J. D’Souza, F. Grynszpan and P.E. Dawson. The 66th Annual Meeting of the Israel Chem. Soc. David –Intercontinental Hotel, Tel-Aviv, Israel, pp. 85. February 5-6, 2001.
  36. Stereochemistry of a Spherand-Type Calixarene.
    By K. Agbaria, S.E. Biali, V. Böhmer, J. Bern, Sh. Cohen, M. Frings, F. Grynszpan, J.McB. Harrowfield, A.N. Sobolev and I. Thondorf. The 66th Annual Meeting of the Israel Chem. Soc. David –Intercontinental Hotel, Tel-Aviv, Israel, pp. 163. February 5-6, 2001.
  37. The Aldolase Antibody-Rhodopsin Analogy.
    By F. Grynszpan, and E. Keinan. The 217th ACS National Meeting, Anaheim, California, pp. ORGN 074, March 21-25, 1999.
  38. Towards Retinoid Receptors Emulating Antibodies.
    By F. Grynszpan, A. Angulo, F. García del Rey, P. Ghazal and E. Keinan. The 62th Annual Meeting of the IsraelChem.Soc.TechnionCity, Haifa, Israel, pp. 274. February 3-5, 1997.
  39. An Efficient Sol-Gel Reactor for Antibody Catalyzed Transformations.
    By D. Shabat, F. Grynszpan, S. Saphier, A. Turniansky, D. Avnir and E. Keinan. The 62th Annual Meeting of the IsraelChem.Soc.TechnionCity, Haifa, Israel. pp. 271. February 3-5, 1997.
  40. Perturbing the Coordination Sphere of a TransitionState Metal Complex with Antibodies.
    By F. Grynszpan, D. Shabat, P. Ghosh, S. Kumar, S.C. Sinha, J. Li, L. Noodelman and E. Keinan. The 62th Annual Meeting of the IsraelChem.Soc.TechnionCity, Haifa, Israel. pp. 270. February 3-5, 1997.
  41. Alkylidene Bridged Calixarenes, Synthesis and Conformational Properties.
    By C. Grüttner, W. Vogt, V. Böhmer, S. E. Biali, F. Grynszpan and I. Thondorf. XX International Symposium on Macrocyclic Chemistry. Jerusalem, Israel, pp 30, July 2-7, 1995.
  42. Synthesis and Reactions of Large-Ring Spirodienone Calixarene Derivatives.
    By F. Grynszpan, O. Aleksiuk and S.E. Biali. XX International Symposium on Macrocyclic Chemistry. Jerusalem, Israel, pp 3, July 2-7, 1995.
  43. The Spirodienone Route for the Intraannular Modification of Calixarenes.
    By O. Aleksiuk, F. Grynszpan and S.E. Biali. Third International Calixarene Conference. TexasChristianUniversity, Fort Worth, Texas, USA. May 21-25, pp 9-20, 1995.
  44. Diffusion Coefficients of p-tert-butylcalix[4]arenes Derivatives by PGSE NMR Technique.
    By O. Mayzel, O. Aleksiuk, F. Grynszpan, S.E. Biali, and Y. Cohen. The 60th Annual Meeting of the Israel Chem. Soc. The Weizmann Institute of Sciences. Israel. pp 90. February 7-8, 1995.
  45. Calixarenes with Alkylidene Bridges (II).
    By C. Grüttner, W. Vogt, V. Böhmer, S. E. Biali and F. Grynszpan. Supramolecular Chemistry. Mainz, Germany. pp 18, section 5. August 11-16,1994.
  46. Calixarenes with Alkylidene Bridges (I).
    By C. Grüttner, W. Vogt, V. Böhmer, S. E. Biali and F. Grynszpan. The International Symposium on Recognition Processes. Birmingham. U. K. pp 38. July 24-29, 1994.
  47. Large Ring Spirodienone Calix[n]arenes Derivatives.
    By F. Grynszpan and S.E. Biali. The 59th Annual Meeting of the Israel Chem. Soc. Ben Gurion Univ. Beer Sheva, Israel. pp. 114. January 31 and February 1, 1994.
  48. The Chemistry of the Monospirodienone Derivative of p-tert-Butylcalix[4]arene.
    By O. Aleksiuk, F. Grynszpan and S.E. Biali. Second Workshop on Calixarenes and Related
    Compounds, June 2-4, 1993, Kurume, Japan. Abstract, PS/A-19.
  49. Stereodynamics of Intraannular-Substituted Calixarenes.
    By F. Grynszpan, O. Aleksiuk and S.E. Biali. The 58th Annual Meeting of the Israel Chem. Soc. Bar-Ilan Univ. Tel-Aviv, Israel. February 17-18, 1993.
  50. Synthesis of Mono- and 1,2-Disubstituted Calixarenes via a Monospiro-dienone-calix[4]arene Derivative.
    By O. Aleksiuk, F. Grynszpan and S.E. Biali. The 58th Annual Meeting of the Israel Chem. Soc. Bar-Ilan Univ. Tel-Aviv, Israel. February 17-18, 1993.
  51. Spirodienone Derivatives of Calix[4]arenes.
    By F. Grynszpan, O. Aleksiuk, A.M. Litwak and S.E. Biali. XVII International Symposium on Macrocyclic Chemistry. Provo, Utah, USA, pp. 9. August 9-14, 1992.
  52. OH-Depleted Calixarenes.
    By F. Grynszpan and S.E. Biali, Workshop on Calixarenes and related Compounds. J. GutenbergUniv.Mainz, Germany. August 28-30. 1991.
  53. Mechanistic Studies of the Reductive Cleavage of Calix[4]arene Derivatives.
    By F. Grynszpan and S.E. Biali, The 56th Annual Meeting of the Israel Chem. Soc. Jerusalem Univ. Jerusalem, Israel. pp. 97. February 11-12, 1991.
  54. Relative Importance of the Complete OH-Array in the Conformation and Rigidity of p-t-Bu Calix[4]arenes.
    By F. Grynszpan, Z. Goren and S.E. Biali. 10th IUPAC Conference on Physical Organic Chemistry. TechnionCity, Haifa, Israel. P.A. A-38. August 5-10, 1990.
  55. Synthesis of OH-Depleted Calix[4]arenes.
    By F. Grynszpan, Z. Goren, N. Dinoor and S.E. Biali. The 55th Annual Meeting of the Israel Chem. Soc. Tel-Aviv Univ. Tel-Aviv, Israel. 28-B, February 11-12, 1990.
  1. BENZOFURAN DERIVATIVES WITH THERAPEUTIC ACTIVITIES
    Inventors: YACOVAN, AVIHAI (IL); GRYNSZPAN, FLAVIO (IL); AIZIKOVICH, ALEXANDER (IL); BRODY, MARCUS STEPHEN (US); BAR-JOSEPH, AVI (IL); MEILIN, SIGAL (IL).
    Publication number: WO2006129318
    Publication date: 2006-12-07
  2. TETRACYCLIC BENZOFURAN DERIVATIVES WITH THERAPEUTIC ACTIVITIES
    Inventors: YACOVAN, AVIHAI (IL); GARZON, AARON (IL); GRYNSZPAN, FLAVIO (IL); BAR-JOSEPH, AVI (IL); MEILIN, SIGAL (IL).
    Publication number: WO200702063
    Publication date: 2007-02-22
  3. BENZOXAZINE DERIVATIVES WITH THERAPEUTIC INDICATIONS
    Inventors: YACOVAN, AVIHAI (IL); GRYNSZPAN, FLAVIO (IL); BRODY, MARCUS,
    STEPHEN (US); BAR-JOSEPH, AVI (IL); MEILIN, SIGAL(IL).
  4. SULFONAMIDE DERIVATIVES WITH THERAPEUTIC INDICATIONS.
    Inventors: YACOVAN, AVIHAI (IL); ALROY, IRIS (IL); AIZKOVICH, ALEXANDER (IL); MIRILASHVILI, SIMA(IL); GRYNSZPAN, FLAVIO (IL).
    International patent application WO/2008/075353
    Filing date: 2007–12–19.
  5. MOLECULARLY IMPRINTED SMART POLYMERS (MISPs).
    Inventors: GRYNSZPAN, FLAVIO (IL); PARTOUCHE, ERAN (IL); SHKOULEV, VLADIMIR (IL); NAKASH-OZERI, RACHEL (IL), ZIGELBOIM, ISAAC (IL), GAZAL, SHARON (IL) AND AIZIKOVICH, ALEXANDER (IL).
    US patent application No 61/136,487.
    Filing date: 2009–09–09.
  6. PREPARATION OF BIMANES AND CHLORINATION OF PYRAZOLINONES.
    NEOGI, ISHITA (IN); DAS, PARTHA JYOTI (IN); GRYNSZPAN, FLAVIO (IL).
    UK patent GB2553527 , January 22, 2020
  1. Manual for the General, Analytical and Inorganic Chemistry Laboratory (Ariel U. Ed. 2012). Edited with Prof. D. Meyerstein, Dr. O. Krichbesky and Ms. M. Ovadia.
  2. The 7th National Graduate Student Symposium in Organic Chemistry.By H. Katz, E. Ragozin, and F. Grynszpan. Isr. Chem. Eng. 2, 77-80, (2016). Non peer-reviewed article.
  3. Manual for the Organic Chemistry Laboratory (Ariel U. 2nd Ed. 2017). Edited with Dr. B. Redko.